Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3407920 | 0.78 | LMNA (0.48) | NPC1LMNAMAPTHTTCYP1A2 | |
| SCHEMBL149055 | 0.77 | NPC1 (0.47) | NPC1LMNAMAPTHTTCYP1A2 | |
| SCHEMBL3402387 | 0.74 | LMNA (0.44) | NPC1LMNAMAPTHTTCYP1A2 | |
| SCHEMBL3409035 | 0.74 | MAPT (0.44) | NPC1LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL11577282 | 0.74 | KMT2A (0.63) | NPC1LMNAMAPTHTTCYP1A2 | |
| SCHEMBL3236831 | 0.73 | NPC1 (0.68) | NPC1LMNAMAPTHTTCYP1A2 | |
| SCHEMBL16817090 | 0.73 | NPC1 (0.43) | NPC1LMNAMAPTHTTCYP1A2 | |
| SCHEMBL16817091 | 0.72 | HSD17B10 (0.44) | NPC1MAPTHTTHPGDRAB9A | |
| SCHEMBL1874869 | 0.72 | HPGD (0.79) | NPC1LMNAMAPTHTTCYP1A2 | |
| SCHEMBL27183151 | 0.72 | NPC1 (0.62) | NPC1LMNAMAPTHTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |