Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3408784 | 0.85 | LMNA (0.41) | LMNACYP1A2HPGDCYP2C19PGR | |
| SCHEMBL3407920 | 0.84 | LMNA (0.48) | LMNACYP1A2HPGDCYP2C19PGR | |
| SCHEMBL3409035 | 0.82 | MAPT (0.44) | LMNACYP1A2HPGDCYP2C19PGR | |
| SCHEMBL157543 | 0.79 | NPC1 (0.42) | NPC1RAB9A | |
| SCHEMBL27856157 | 0.79 | NPC1 (0.42) | NPC1RAB9A | |
| SCHEMBL157544 | 0.79 | NPC1 (0.42) | NPC1RAB9A | |
| SCHEMBL157542 | 0.78 | SLC5A2 (0.37) | LMNAABCG2NPC1RAB9ASTING1 | |
| SCHEMBL3409491 | 0.77 | ALDH1A1 (0.43) | LMNACYP1A2HPGDCYP2C19CYP3A4 | |
| SCHEMBL3407747 | 0.77 | CNR2 (0.39) | HPGDCYP3A4KMT2AMEN1MAPT | |
| SCHEMBL149055 | 0.76 | NPC1 (0.47) | LMNACYP1A2HPGDCYP2C19PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |