Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3407920 | 0.89 | LMNA (0.48) | MAPTSMN1; SMN2HIF1ALMNACYP1A2 | |
| SCHEMBL3407763 | 0.84 | ALDH1A1 (0.53) | MAPTSMN1; SMN2LMNACYP1A2PGR | |
| SCHEMBL3402387 | 0.82 | LMNA (0.44) | MAPTSMN1; SMN2HIF1ALMNACYP1A2 | |
| SCHEMBL3402854 | 0.80 | ALDH1A1 (0.48) | MAPTCYP3A4HPGDNPC1RAB9A | |
| SCHEMBL3408784 | 0.80 | LMNA (0.41) | MAPTSMN1; SMN2HIF1ALMNACYP1A2 | |
| SCHEMBL3409107 | 0.80 | GAA (0.44) | MAPTLMNATSHRKMT2AALDH1A1 | |
| SCHEMBL153422 | 0.79 | SLC5A1 (0.44) | NPC1RAB9AKMT2AMEN1ACHE | |
| SCHEMBL153423 | 0.79 | SLC5A1 (0.44) | NPC1RAB9AKMT2AMEN1ACHE | |
| SCHEMBL27856158 | 0.79 | SLC5A1 (0.44) | NPC1RAB9AKMT2AMEN1ACHE | |
| SCHEMBL3402632 | 0.78 | HTT (0.45) | MAPTSMN1; SMN2LMNAHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |