Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1489010 | 1.00 | HDAC1 (0.59) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1489223 | 0.91 | HDAC3 (0.55) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1489222 | 0.91 | HDAC3 (0.55) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1489015 | 0.90 | CYP19A1 (0.51) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1489017 | 0.90 | CYP19A1 (0.51) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1489093 | 0.80 | HDAC1 (0.46) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1489089 | 0.80 | HDAC1 (0.46) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL14161788 | 0.80 | HDAC4 (0.60) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1489165 | 0.79 | MAPT (0.48) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1489163 | 0.79 | MAPT (0.48) | HDAC1HDAC8HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110077305-A1 | 5-LIPOXYGENASE INHIBITORS | FYLOCEL LTD. (GB) | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077305-A1 | 5-LIPOXYGENASE INHIBITORS | ALOX12, ALOX15, ALOX5 | HDAC1 1610/4885HDAC8 2559/4885HDAC3 2267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.