Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.35 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22610214 | 0.74 | NPC1 (0.36) | MAPTCA12GMNNALDH1A1CA1 | |
| SCHEMBL17839030 | 0.74 | NPC1 (0.36) | MAPTCA12GMNNALDH1A1CA1 | |
| SCHEMBL14463311 | 0.73 | MAPT (0.34) | MAPTCA12GMNNALDH1A1CA1 | |
| SCHEMBL8007371 | 0.72 | NPC1 (0.40) | MAPTCA12GMNNALDH1A1CA1 | |
| SCHEMBL677038 | 0.70 | MAPT (0.40) | MAPTCA12GMNNALDH1A1CA1 | |
| SCHEMBL678021 | 0.70 | MAPT (0.40) | MAPTCA12GMNNALDH1A1CA1 | |
| SCHEMBL10291030 | 0.68 | L3MBTL1 (0.36) | MAPTCA12GMNNALDH1A1CA1 | |
| SCHEMBL20690173 | 0.67 | MAPT (0.33) | MAPTCA12GMNNALDH1A1CA1 | |
| SCHEMBL9751037 | 0.67 | MAPT (0.33) | MAPTCA12GMNNALDH1A1CA1 | |
| SCHEMBL6126167 | 0.67 | EPHX1 (0.42) | MAPTCA12GMNNALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834738-B2 | Octahydro-1H-4,7-methano-indene-5-aldehydes and their use in perfume compositions | INTERNATIONAL FLAVORS AND FRAGRANCES INC. | 2017-12-05 | — | — | US | disclosed |
| US-9834738-B2 | Octahydro-1H-4,7-methano-indene-5-aldehydes and their use in perfume compositions | INTERNATIONAL FLAVORS AND FRAGRANCES INC. | 2017-12-05 | — | — | US | disclosed |
| US-9834738-B2 | Octahydro-1H-4,7-methano-indene-5-aldehydes and their use in perfume compositions | INTERNATIONAL FLAVORS AND FRAGRANCES INC. | 2017-12-05 | — | — | US | disclosed |
| EP-2589649-B1 | Octahydro-1H-4,7-methano-indene-5-aldehydes and their use in perfume compositions | INT FLAVORS & FRAGRANCES INC (US) | 2015-11-25 | — | — | EP | disclosed |
| EP-2589649-B1 | Octahydro-1H-4,7-methano-indene-5-aldehydes and their use in perfume compositions | INT FLAVORS & FRAGRANCES INC (US) | 2015-11-25 | — | — | EP | disclosed |
| US-20140107220-A1 | OCTAHYDRO-1H-4,7-METHANO-INDENE-5-ALDEHYDES AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-04-17 | — | — | US | disclosed |
| US-20140107220-A1 | OCTAHYDRO-1H-4,7-METHANO-INDENE-5-ALDEHYDES AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-04-17 | — | — | US | disclosed |
| US-20140107221-A1 | OCTAHYDRO-1H-4,7-METHANO-INDENE-5-ALDEHYDES AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-04-17 | — | — | US | disclosed |
| US-20140107220-A1 | OCTAHYDRO-1H-4,7-METHANO-INDENE-5-ALDEHYDES AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-04-17 | — | — | US | disclosed |
| US-20140107221-A1 | OCTAHYDRO-1H-4,7-METHANO-INDENE-5-ALDEHYDES AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-04-17 | — | — | US | disclosed |
| US-20140107221-A1 | OCTAHYDRO-1H-4,7-METHANO-INDENE-5-ALDEHYDES AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-04-17 | — | — | US | disclosed |
| US-8633144-B2 | Octahydro-1H-4,7-methano-indene-5-aldehydes and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-01-21 | — | — | US | disclosed |
| US-8633144-B2 | Octahydro-1H-4,7-methano-indene-5-aldehydes and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-01-21 | — | — | US | disclosed |
| US-8633144-B2 | Octahydro-1H-4,7-methano-indene-5-aldehydes and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2014-01-21 | — | — | US | disclosed |
| EP-2589649-A1 | Octahydro-1H-4,7-methano-indene-5-aldehydes and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-05-08 | — | — | EP | disclosed |
| EP-2589649-A1 | Octahydro-1H-4,7-methano-indene-5-aldehydes and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2013-05-08 | — | — | EP | disclosed |
| US-20130109761-A1 | OCTAHYDRO-1H-4,7-METHANO-INDENE-5-ALDEHYDES AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2013-05-02 | — | — | US | disclosed |
| US-20130109761-A1 | OCTAHYDRO-1H-4,7-METHANO-INDENE-5-ALDEHYDES AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2013-05-02 | — | — | US | disclosed |
| US-20130109761-A1 | OCTAHYDRO-1H-4,7-METHANO-INDENE-5-ALDEHYDES AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107220-A1 | OCTAHYDRO-1H-4,7-METHANO-INDENE-5-ALDEHYDES AND THEIR USE IN PERFUME COMPOSITIONS | ADH5, TRPA1, ADH1A | MAPT 1538/4885CA12 4268/4885GMNN 2443/4885 |
| US-20130109761-A1 | OCTAHYDRO-1H-4,7-METHANO-INDENE-5-ALDEHYDES AND THEIR USE IN PERFUME COMPOSITIONS | MSMO1, ADH5, TRPA1 | MAPT 1745/4885CA12 4158/4885GMNN 2302/4885 |
| US-20140107221-A1 | OCTAHYDRO-1H-4,7-METHANO-INDENE-5-ALDEHYDES AND THEIR USE IN PERFUME COMPOSITIONS | MSMO1, TRPA1, ADH5 | MAPT 1542/4885CA12 4381/4885GMNN 2200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.