Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1686254 | 0.97 | TSHR (0.47) | MEN1LMNAKMT2ATSHRNFKB1 | |
| Bromide SCHEMBL8461151 | 0.93 | MEN1 (0.47) | MEN1LMNAKMT2ATSHRNFKB1 | |
| Hydrochloric Acid SCHEMBL853896 | 0.93 | KDM4E (0.50) | MEN1LMNAKMT2ATSHRNFKB1 | |
| Water SCHEMBL2032857 | 0.93 | TSHR (0.44) | MEN1LMNAKMT2ATSHRNFKB1 | |
| SCHEMBL1686196 | 0.90 | TSHR (0.47) | MEN1LMNAKMT2ATSHRNFKB1 | |
| SCHEMBL476985 | 0.90 | TSHR (0.47) | MEN1LMNAKMT2ATSHRNFKB1 | |
| SCHEMBL20175892 | 0.88 | SLC22A1 (0.50) | MEN1LMNAKMT2ATSHRNFKB1 | |
| SCHEMBL28465660 | 0.88 | SLC22A1 (0.50) | MEN1LMNAKMT2ATSHRNFKB1 | |
| SCHEMBL10002125 | 0.87 | TSHR (0.44) | MEN1LMNAKMT2ATSHRNFKB1 | |
| Fluoride Ion SCHEMBL17870608 | 0.87 | TSHR (0.44) | MEN1LMNAKMT2ATSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150211130-A1 | ANTI-CORROSIVE AGENT FOR WASHING OF METAL WITH ACID, DETERGENT SOLUTION COMPOSITION, AND METHOD FOR WASHING OF METAL | NITTO BOSEKI CO LTD (JP) | 2015-07-30 | — | — | US | disclosed |
| US-20130109607-A1 | ANTI-CORROSIVE AGENT FOR WASHING OF METAL WITH ACID, DETERGENT SOLUTION COMPOSITION, AND METHOD FOR WASHING OF METAL | NITTO BOSEKI CO., LTD. (JP) | 2013-05-02 | — | — | US | disclosed |