Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CPT1A | P50416 | 1/20 | 0.43 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1488946 | 0.89 | ALOX5 (0.49) | MEN1KMT2ATHRBHDAC8TDP1 | |
| SCHEMBL1488869 | 0.87 | CES1 (0.51) | MEN1KMT2ATHRBHDAC8TDP1 | |
| SCHEMBL1489203 | 0.87 | CES1 (0.51) | MEN1KMT2ATHRBHDAC8TDP1 | |
| SCHEMBL1489233 | 0.81 | PGR (0.46) | THRBHDAC8TDP1ALOX5EPHX2 | |
| SCHEMBL12831241 | 0.80 | CYP19A1 (0.57) | CYP19A1MEN1KMT2ATHRBHDAC8 | |
| SCHEMBL1489321 | 0.79 | ALOX5 (0.49) | HDAC8ALOX5EPHX2MAPTHDAC1 | |
| SCHEMBL1489019 | 0.78 | CES1 (0.49) | CYP19A1THRBHDAC8TDP1MAPT | |
| SCHEMBL1488976 | 0.78 | CES1 (0.49) | CYP19A1THRBHDAC8TDP1MAPT | |
| SCHEMBL1489015 | 0.76 | CYP19A1 (0.51) | CYP19A1MEN1KMT2ATHRBHDAC8 | |
| SCHEMBL1489017 | 0.76 | CYP19A1 (0.51) | CYP19A1MEN1KMT2ATHRBHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110077305-A1 | 5-LIPOXYGENASE INHIBITORS | FYLOCEL LTD. (GB) | 2011-03-31 | — | — | US | disclosed |
| US-20110077305-A1 | 5-LIPOXYGENASE INHIBITORS | FYLOCEL LTD. (GB) | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077305-A1 | 5-LIPOXYGENASE INHIBITORS | ALOX12, ALOX15, ALOX5 | CYP19A1 314/4885MEN1 3066/4885KMT2A 2920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.