Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 8/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.39 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1489870 | 1.00 | L3MBTL3 (0.39) | L3MBTL3L3MBTL1MBTD1HTR6CYP2D6 | |
| SCHEMBL1489973 | 1.00 | L3MBTL3 (0.39) | L3MBTL3L3MBTL1MBTD1HTR6CYP2D6 | |
| SCHEMBL667276 | 0.98 | L3MBTL1 (0.40) | L3MBTL3L3MBTL1MBTD1HTR6ALDH1A1 | |
| SCHEMBL477164 | 0.98 | L3MBTL1 (0.40) | L3MBTL3L3MBTL1MBTD1HTR6ALDH1A1 | |
| SCHEMBL667548 | 0.98 | L3MBTL1 (0.40) | L3MBTL3L3MBTL1MBTD1HTR6ALDH1A1 | |
| SCHEMBL1664709 | 0.93 | — | — | |
| SCHEMBL2008594 | 0.88 | L3MBTL3 (0.38) | L3MBTL3L3MBTL1MBTD1HTR6CYP2D6 | |
| SCHEMBL4166916 | 0.86 | HTR6 (0.41) | L3MBTL3L3MBTL1MBTD1HTR6 | |
| SCHEMBL3933942 | 0.86 | L3MBTL1 (0.39) | L3MBTL3L3MBTL1MBTD1HTR6ALDH1A1 | |
| SCHEMBL3549709 | 0.85 | L3MBTL3 (0.41) | L3MBTL3L3MBTL1MBTD1HTR6CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888565-B1 | 2, 6-DI (HETERO) ARYL -4-AMIDO-PYRIMIDINES AS ADENOSINE RECEPTOR ANTAGONISTS | ALMIRALL SA (ES) | 2011-03-23 | — | — | EP | disclosed |