Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 8/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3933942 | 0.98 | L3MBTL1 (0.39) | L3MBTL3L3MBTL1HTR6MBTD1 | |
| SCHEMBL4166916 | 0.89 | HTR6 (0.41) | L3MBTL3L3MBTL1HTR6MBTD1PHGDH | |
| SCHEMBL1489616 | 0.88 | L3MBTL3 (0.39) | L3MBTL3L3MBTL1HTR6MBTD1CYP2D6 | |
| SCHEMBL1833709 | 0.88 | L3MBTL3 (0.34) | L3MBTL3L3MBTL1HTR6MBTD1 | |
| SCHEMBL1489870 | 0.88 | L3MBTL3 (0.39) | L3MBTL3L3MBTL1HTR6MBTD1CYP2D6 | |
| SCHEMBL1489973 | 0.88 | L3MBTL3 (0.39) | L3MBTL3L3MBTL1HTR6MBTD1CYP2D6 | |
| SCHEMBL174054 | 0.86 | HTR6 (0.42) | L3MBTL3L3MBTL1HTR6MBTD1CYP2D6 | |
| SCHEMBL667276 | 0.86 | L3MBTL1 (0.40) | L3MBTL3L3MBTL1HTR6MBTD1 | |
| SCHEMBL667548 | 0.86 | L3MBTL1 (0.40) | L3MBTL3L3MBTL1HTR6MBTD1 | |
| SCHEMBL477164 | 0.86 | L3MBTL1 (0.40) | L3MBTL3L3MBTL1HTR6MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2506855-A1 | ANTICANCER COMPOUNDS AND SCREENING METHOD | Harbor BioSciences, Inc. (US) | 2012-10-10 | — | — | EP | claimed |
| WO-2011066582-A1 | ANTICANCER COMPOUNDS AND SCREENING METHOD | HARBOR BIOSCIENCES, INC. (US) | 2011-06-03 | — | — | WO | claimed |
| EP-2506855-A1 | ANTICANCER COMPOUNDS AND SCREENING METHOD | Harbor BioSciences, Inc. (US) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011066582-A1 | ANTICANCER COMPOUNDS AND SCREENING METHOD | HARBOR BIOSCIENCES, INC. (US) | 2011-06-03 | — | — | WO | disclosed |