Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | CA12 | O43570 | 3/20 | 0.66 |
| ▸ | CA1 | P00915 | 3/20 | 0.66 |
| ▸ | CA2 | P00918 | 3/20 | 0.66 |
| ▸ | CA3 | P07451 | 3/20 | 0.66 |
| ▸ | CA4 | P22748 | 3/20 | 0.66 |
| ▸ | CA6 | P23280 | 3/20 | 0.66 |
| ▸ | CA5A | P35218 | 3/20 | 0.66 |
| ▸ | CA7 | P43166 | 3/20 | 0.66 |
| ▸ | CA9 | Q16790 | 3/20 | 0.66 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.66 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.66 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.66 |
| ▸ | DPP4 | P27487 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14898184 | 0.86 | KDM4E (0.66) | KDM4EPTPN1HSD17B10CA12CA1 | |
| SCHEMBL10892522 | 0.86 | PTPN1 (0.76) | KDM4EPTPN1HSD17B10CA12CA1 | |
| SCHEMBL9688131 | 0.86 | PTPN1 (0.76) | KDM4EPTPN1HSD17B10CA12CA1 | |
| SCHEMBL15780784 | 0.85 | PTGS1 (0.67) | KDM4EPTPN1HSD17B10CA12CA1 | |
| SCHEMBL1603721 | 0.81 | PTPN1 (0.62) | KDM4EPTPN1HSD17B10CA12CA1 | |
| SCHEMBL1603718 | 0.81 | PTPN1 (0.62) | KDM4EPTPN1HSD17B10CA12CA1 | |
| SCHEMBL11588431 | 0.80 | MAPT (0.77) | KDM4EPTPN1HSD17B10CA12CA1 | |
| Caffeic Acid SCHEMBL3682144 | 0.80 | KDM4E (1.00) | KDM4EPTPN1HSD17B10CA12CA1 | |
| Caffeic Acid SCHEMBL21114743 | 0.80 | KDM4E (1.00) | KDM4EPTPN1HSD17B10CA12CA1 | |
| Caffeic Acid SCHEMBL23358 | 0.80 | KDM4E (1.00) | KDM4EPTPN1HSD17B10CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200354319-A1 | MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | UNIV CORNELL (US) | 2020-11-12 | — | — | US | disclosed |
| US-20140194383-A1 | MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | CORNELL UNIVERSITY (US) | 2014-07-10 | — | — | US | disclosed |
| US-20140161729-A1 | COFLUORONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2014-06-12 | — | — | US | disclosed |
| US-20140161729-A1 | COFLUORONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2014-06-12 | — | — | US | disclosed |
| WO-2013058824-A1 | MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | CORNELL UNIVERSITY (US) | 2013-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140161729-A1 | COFLUORONS AND METHODS OF MAKING AND USING THEM | TNFSF11, CD14, TNFRSF1A | KDM4E 4722/4885PTPN1 4538/4885HSD17B10 2940/4885 |
| US-20200354319-A1 | MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | CALCOCO2, MDN1, MBNL1 | KDM4E 4611/4885PTPN1 2829/4885HSD17B10 4404/4885 |
| US-20140194383-A1 | MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | CALCOCO2, MDN1, MBNL1 | KDM4E 4611/4885PTPN1 2829/4885HSD17B10 4404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.