Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.37 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814732 | 0.97 | KEAP1 (0.46) | KEAP1MAPK1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1843566 | 0.95 | KEAP1 (0.49) | KEAP1MAPK1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL3584707 | 0.87 | ALOX15 (0.37) | ALDH1A1MAPTL3MBTL1ALOX15HSD17B10 | |
| SCHEMBL6984223 | 0.85 | ADRB1 (0.49) | ALDH1A1HSD17B10KDM4EHTR1ADRD2 | |
| SCHEMBL3579186 | 0.82 | ALDH1A1 (0.39) | MAPK1ALDH1A1MAPTL3MBTL1ALOX15 | |
| SCHEMBL29557633 | 0.79 | KEAP1 (0.44) | KEAP1L3MBTL1GAANPC1TNKS | |
| SCHEMBL138181 | 0.79 | KEAP1 (0.44) | KEAP1L3MBTL1GAANPC1TNKS | |
| SCHEMBL2945343 | 0.78 | UCHL1 (0.36) | MAPTKDM4E | |
| SCHEMBL4543332 | 0.77 | DDB1 (0.50) | MAPTL3MBTL1P2RX7KMT2AMEN1 | |
| SCHEMBL3361698 | 0.77 | MGLL (0.43) | P2RX7TNKSKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788498-B1 | PHENYLOXAZOLIDINONE ANTIMICROBIALS | UPJOHN CO (US) | 2001-08-16 | — | — | EP | disclosed |
| CN-1068325-C | phenyl oxazolidinone antibacterial agents | PHARMACIA & UPJOHN CO LLC (US) | 2001-07-11 | — | — | CN | disclosed |
| US-5883093-A | TREATING MICROBIAL INFECTIONS IN WARM BLOODED ANIMALS, INCLUDING HUMANS | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| CN-1162312-A | Phenyloxazolidinone antimicrobials | PHARMACIA & UPJOHN CO LLC (US) | 1997-10-15 | — | — | CN | disclosed |
| EP-0788498-A1 | PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996013502-A1 | PHENYLOXAZOLIDINONE ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1996-05-09 | — | — | WO | disclosed |