Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071933 | 1.00 | MAOB (0.42) | MAOBSLC6A2SLC6A4IDO1SLC6A3 | |
| SCHEMBL2668590 | 0.87 | ALDH1A1 (0.41) | MAOBALDH1A1 | |
| SCHEMBL9071949 | 0.87 | ALDH1A1 (0.41) | MAOBALDH1A1 | |
| SCHEMBL12204361 | 0.85 | TRPM8 (0.39) | MAOBSLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL9071903 | 0.84 | KMT2A (0.42) | MAOBSLC6A2SLC6A4IDO1MAOA | |
| SCHEMBL2669500 | 0.84 | KMT2A (0.42) | MAOBSLC6A2SLC6A4IDO1MAOA | |
| SCHEMBL2668708 | 0.84 | SLC6A2 (0.37) | SLC6A2SLC6A4 | |
| SCHEMBL9071938 | 0.83 | GAA (0.47) | SLC6A2SLC6A4IDO1ALDH1A1 | |
| SCHEMBL14899708 | 0.83 | TRPV1 (0.35) | MAOBALDH1A1 | |
| SCHEMBL2668517 | 0.82 | PYGL (0.41) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904467-B1 | Urea glucokinase activators | NOVO NORDISK AS (DK) | 2013-05-01 | — | — | EP | disclosed |