Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 6/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071949 | 0.91 | ALDH1A1 (0.41) | KCNH2SCN3ATRPM8ALDH1A1LMNA | |
| SCHEMBL2668590 | 0.91 | ALDH1A1 (0.41) | KCNH2SCN3ATRPM8ALDH1A1LMNA | |
| SCHEMBL2668607 | 0.88 | RAB9A (0.34) | TRPV1KCNH2TRPM8ALDH1A1LMNA | |
| SCHEMBL12204361 | 0.83 | TRPM8 (0.39) | TRPM8ALDH1A1MAOB | |
| SCHEMBL9071933 | 0.83 | MAOB (0.42) | ALDH1A1MAOB | |
| SCHEMBL14899706 | 0.83 | MAOB (0.42) | ALDH1A1MAOB | |
| SCHEMBL13486496 | 0.83 | HTR2A (0.39) | MAOB | |
| SCHEMBL9071903 | 0.82 | KMT2A (0.42) | TRPM8ALDH1A1LMNAMAOBRAB9A | |
| SCHEMBL2669500 | 0.82 | KMT2A (0.42) | TRPM8ALDH1A1LMNAMAOBRAB9A | |
| SCHEMBL2668708 | 0.82 | SLC6A2 (0.37) | TRPV1KCNH2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904467-B1 | Urea glucokinase activators | NOVO NORDISK AS (DK) | 2013-05-01 | — | — | EP | disclosed |