Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.68 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.68 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.62 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | RARB | P10826 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13845292 | 0.93 | LTA4H (0.68) | LTA4HNR5A1ABCG2TSHRSMN1; SMN2 | |
| SCHEMBL8769969 | 0.93 | TP53 (0.68) | TSHRSMN1; SMN2TP53PLA2G4BL3MBTL1 | |
| SCHEMBL17203727 | 0.89 | TP53 (0.74) | NR5A1TSHRTP53PLA2G4BL3MBTL1 | |
| SCHEMBL15154875 | 0.87 | TP53 (0.77) | NR5A1TSHRTP53PLA2G4BL3MBTL1 | |
| SCHEMBL6705357 | 0.87 | TP53 (0.77) | NR5A1TSHRTP53PLA2G4BL3MBTL1 | |
| SCHEMBL1623628 | 0.87 | TP53 (0.77) | NR5A1TSHRTP53PLA2G4BL3MBTL1 | |
| SCHEMBL18302060 | 0.87 | TP53 (0.77) | NR5A1TSHRTP53PLA2G4BL3MBTL1 | |
| SCHEMBL8769734 | 0.87 | TP53 (0.77) | NR5A1TSHRTP53PLA2G4BL3MBTL1 | |
| SCHEMBL533825 | 0.87 | TP53 (0.77) | NR5A1TSHRTP53PLA2G4BL3MBTL1 | |
| SCHEMBL9736442 | 0.87 | LMNA (0.67) | LTA4HNR5A1TSHRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016196342-A1 | TETRASUBSTITUTED ALKENE COMPOUNDS AND THEIR USE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2016-12-08 | — | — | WO | disclosed |
| US-9309211-B2 | Arylalkene derivatives and use thereof as selective estrogen receptor modulators | CENTAURUS BIOPHARMA CO., LTD. (CN) | 2016-04-12 | — | — | US | disclosed |
| US-20130109758-A1 | BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109758-A1 | BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | SHBG, KLK3, HSD17B11 | LTA4H 2660/4885NR5A1 19/4885ABCG2 834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.