SCHEMBL14902188

SCHEMBL14902188

CCOC(=O)C(=O)CC(=O)N1CCC(O)CC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.48
MAPT P10636 3/20 0.46
TDP1 Q9NUW8 1/20 0.44
ALDH1A1 P00352 5/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
THRB P10828 1/20 0.42
ATM Q13315 1/20 0.42
POLB P06746 2/20 0.40
TSHR P16473 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
NOS3 P29474 1/20 0.40
NOS2 P35228 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PKM P14618 1/20 0.40
KDM4E B2RXH2 2/20 0.39
ALOX15 P16050 1/20 0.38
TP53 P04637 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16653579 0.83 ALOX15 (0.54) GAAMAPTTDP1ALDH1A1L3MBTL1
SCHEMBL15823542 0.83 POLB (0.44) GAAMAPTTDP1ALDH1A1L3MBTL1
SCHEMBL15821883 0.80 GAA (0.42) GAAMAPTALDH1A1L3MBTL1THRB
SCHEMBL2419143 0.79 TSHR (0.59) GAAMAPTALDH1A1L3MBTL1POLB
SCHEMBL20930119 0.79 NPC1 (0.33) GAATDP1ALDH1A1
SCHEMBL1219954 0.77 GAA (0.65) GAAMAPTTDP1ALDH1A1L3MBTL1
SCHEMBL12322935 0.74 ALDH1A1 (0.45) GAAMAPTTDP1ALDH1A1L3MBTL1
SCHEMBL2416369 0.74 EPHX2 (0.44) TDP1ALDH1A1HTT
SCHEMBL15821286 0.74 ALDH1A1 (0.36) TDP1ALDH1A1NOS3NOS2SMN1; SMN2
SCHEMBL2413139 0.73 ALDH1A1 (0.42) TDP1ALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3473098-A1 COMPOSITION FOR REGULATING PLANT GROWTH, METHOD FOR TREATING PLANTS THEREWITH, AND ACTIVE INGREDIENT THEREOF Gorbunov, Sergei Valeryevich (RU) 2019-04-24 EP disclosed
EP-3473098-A1 COMPOSITION FOR REGULATING PLANT GROWTH, METHOD FOR TREATING PLANTS THEREWITH, AND ACTIVE INGREDIENT THEREOF Gorbunov, Sergei Valeryevich (RU) 2019-04-24 EP disclosed
US-9943498-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2018-04-17 US disclosed
US-9943498-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2018-04-17 US disclosed
EP-2934508-B1 FE(III)-2-OXO-BUTANEDIAMIDE COMPLEXES FOR TREATMENT AND PROPHYLAXIS OF IRON DEFICIENCIES AND ANEMIA VIFOR (INTERNATIONAL) AG (CH) 2017-12-06 EP disclosed
US-20160310459-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias VIFOR (INTERNATIONAL) AG (CH) 2016-10-27 US disclosed
US-20160310459-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias VIFOR (INTERNATIONAL) AG (CH) 2016-10-27 US disclosed
US-9452152-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2016-09-27 US disclosed
US-9394324-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2016-07-19 US disclosed
US-9394324-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2016-07-19 US disclosed
US-20150313864-A1 Fe(III) Complex Compounds for the Treatment and Prophylaxis of Iron Deficiency Symptoms and Iron Deficiency Anemias VIFOR (INTERNATIONAL) AG (CH) 2015-11-05 US disclosed
EP-2934508-A1 FE(III) COMPLEX COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF IRON DEFICIENCY SYMPTOMS AND IRON DEFICIENCY ANEMIA Vifor (International) AG (CH) 2015-10-28 EP disclosed
WO-2014096193-A1 FE(III) COMPLEX COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF IRON DEFICIENCY SYMPTOMS AND IRON DEFICIENCY ANEMIA VIFOR (INTERNATIONAL) AG (CH) 2014-06-26 WO disclosed
US-20130109662-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias VIFOR (INTERNATIONAL) AG (CH) 2013-05-02 US disclosed
US-20130109662-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias VIFOR (INTERNATIONAL) AG (CH) 2013-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130109662-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias FECH, SDHB, SLC40A1 GAA 215/4885MAPT 3910/4885TDP1 4796/4885
US-20160310459-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias FECH, SDHB, SLC40A1 GAA 215/4885MAPT 3910/4885TDP1 4796/4885
US-20150313864-A1 Fe(III) Complex Compounds for the Treatment and Prophylaxis of Iron Deficiency Symptoms and Iron Deficiency Anemias FECH, SDHB, SLC40A1 GAA 215/4885MAPT 3910/4885TDP1 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.