SCHEMBL1490337

SCHEMBL1490337

C=C(C)C(=O)O[SiH](CCC)C(OCC)OCC

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.36
TSHR P16473 3/20 0.35
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2491695 0.90 TSHR (0.40) THRBTSHRALDH1A1
SCHEMBL27764596 0.86 THRB (0.38) THRBTSHRALDH1A1
SCHEMBL584057 0.85 ALDH1A1 (0.38) THRBTSHRALDH1A1
SCHEMBL1274035 0.81 TSHR (0.33) THRBTSHRALDH1A1
SCHEMBL10430813 0.78 TSHR (0.36) THRBTSHRALDH1A1
SCHEMBL27926533 0.77 THRB (0.39) THRBTSHRALDH1A1
SCHEMBL9190103 0.72
SCHEMBL986237 0.72
SCHEMBL1846279 0.71 TSHR (0.47) THRBTSHRALDH1A1
SCHEMBL27533348 0.71 TSHR (0.51) THRBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4085100-A1 CHEMICAL RESISTANT POLYCARBONATE BLEND COMPOSITIONS Covestro LLC (US) 2022-11-09 EP disclosed
WO-2017046126-A1 IMPACT MODIFIED POLYCARBONATE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2017-03-23 WO disclosed
EP-2935499-A1 METHOD FOR REMOVING PERMEATES FROM FLAT STRUCTURES, AND CORREPSONDING ADHESIVE TAPE Tesa SE (DE) 2015-10-28 EP disclosed
WO-2014095385-A1 METHOD FOR REMOVING PERMEATES FROM FLAT STRUCTURES, AND CORREPSONDING ADHESIVE TAPE TESA SE (DE) 2014-06-26 WO disclosed
EP-2294136-A2 IMPACT RESISTANT, FLAME RETARDANT THERMOPLASTIC MOLDING COMPOSITION Bayer MaterialScience LLC (US) 2011-03-16 EP disclosed
EP-2217661-A2 IMPACT RESISTANT, FLAME RETARDANT THERMOPLASTIC MOLDING COMPOSITION Bayer MaterialScience LLC (US) 2010-08-18 EP disclosed
WO-2010008484-A2 IMPACT RESISTANT, FLAME RETARDANT THERMOPLASTIC MOLDING COMPOSITION BAYER MATERIALSCIENCE LLC (US) 2010-01-21 WO disclosed
WO-2009105087-A2 IMPACT RESISTANT, FLAME RETARDANT THERMOPLASTIC MOLDING COMPOSITION BAYER MATERIAL SCIENCE LLC (US) 2009-08-27 WO disclosed
EP-1394217-A2 Polymeric compositions useful in plastic resins ROHM AND HAAS COMPANY (US) 2004-03-03 EP disclosed
EP-1394209-A1 Polymeric compositions useful in plastic resins ROHM AND HAAS COMPANY (US) 2004-03-03 EP disclosed
US-5196260-A Polysiloxanes with vinyl groups copolymerized with vinyl monomer, washfastness, whiteness CIBA-GEIGY CORPORATION (US) 1993-03-23 US disclosed
EP-0308871-A2 Thermoplastic polyester resin composition MITSUBISHI RAYON CO., LTD. (JP) 1989-03-29 EP disclosed