Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 16/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 16/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14903957 | 0.83 | RAB9A (0.38) | PDCD1CD274RAB9ARCE1PTGS1 | |
| SCHEMBL14903962 | 0.77 | CD274 (0.46) | PDCD1CD274 | |
| SCHEMBL14903979 | 0.77 | MTNR1A (0.43) | CYP1A2CYP3A4CYP2C9CYP2C19PTGS1 | |
| SCHEMBL14904027 | 0.73 | PDCD1 (0.39) | PDCD1CD274 | |
| SCHEMBL14903984 | 0.73 | FYN (0.38) | PDCD1CD274 | |
| SCHEMBL14903976 | 0.72 | PDCD1 (0.53) | PDCD1CD274CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL358303 | 0.69 | CD274 (1.00) | PDCD1CD274PTGS1EPHX1 | |
| SCHEMBL29558512 | 0.69 | CD274 (1.00) | PDCD1CD274PTGS1EPHX1 | |
| SCHEMBL14926982 | 0.69 | CD274 (0.45) | PDCD1CD274 | |
| SCHEMBL11933621 | 0.68 | CA12 (0.44) | CYP2C9CYP2C19RAB9ARCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109713-A1 | ANTIMICROBIAL AGENTS | RPS4X, RPS4Y1, MRPL21 | PDCD1 4650/4885CD274 4594/4885CYP1A2 3899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.