SCHEMBL14907349

SCHEMBL14907349

Cc1cccc(C)c1-c1cc(Br)cc(Br)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
MAPK1 P28482 1/20 0.41
SRC P12931 2/20 0.41
MAOB P27338 2/20 0.41
IKBKB O14920 1/20 0.41
GRIA1 P42261 3/20 0.40
CACNG8 Q8WXS5 3/20 0.40
HTR7 P34969 1/20 0.39
MAOA P21397 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1990106 0.95 ALDH1A1 (0.41) ALDH1A1MAPK1SRCMAOBIKBKB
SCHEMBL23421117 0.87 GRIA1 (0.38) ALDH1A1MAPK1SRCMAOBIKBKB
SCHEMBL17495238 0.84 IKBKB (0.56) ALDH1A1MAPK1SRCMAOBIKBKB
SCHEMBL24027825 0.81 ALDH1A1 (0.48) ALDH1A1MAPK1SRCMAOBIKBKB
SCHEMBL30213031 0.81 ALDH1A1 (0.48) ALDH1A1MAPK1SRCMAOBIKBKB
SCHEMBL13312937 0.78 MAOA (0.47) ALDH1A1MAPK1SRCMAOBIKBKB
SCHEMBL23369619 0.78 RAPGEF4 (0.38) ALDH1A1MAPK1KDM4EMEN1NPC1
SCHEMBL31621546 0.76 MAOB (0.38) ALDH1A1MAPK1MAOBMAOANPC1
SCHEMBL20662981 0.75 SRC (0.47) ALDH1A1SRCGRIA1CACNG8HTR7
SCHEMBL20684759 0.75 ACHE (0.48) ALDH1A1SRCGRIA1CACNG8HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9825228-B2 Hyperbranched polymers, process for the preparation thereof and use thereof in electronic devices MERCK PATENT GMBH (DE) 2017-11-21 US disclosed
US-9825228-B2 Hyperbranched polymers, process for the preparation thereof and use thereof in electronic devices MERCK PATENT GMBH (DE) 2017-11-21 US disclosed
EP-2771386-B1 HYPERBRANCHED POLYMERS, METHODS FOR PRODUCING SAME, AND USE OF SAME IN ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-03-01 EP disclosed
US-20140339476-A1 HYPERBRANCHED POLYMERS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2014-11-20 US disclosed
US-20140339476-A1 HYPERBRANCHED POLYMERS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2014-11-20 US disclosed
WO-2013060411-A1 HYPERBRANCHED POLYMERS, METHODS FOR PRODUCING SAME, AND USE OF SAME IN ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2013-05-02 WO disclosed