Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.46 |
| ▸ | RARB | P10826 | 2/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14907440 | 0.95 | RARB (0.43) | S1PR1S1PR3RARBPTPN11THRB | |
| SCHEMBL14088541 | 0.81 | FAAH (0.40) | THRBITGB3ITGA2BTSHRCYP2C9 | |
| SCHEMBL14907552 | 0.81 | THRB (0.47) | S1PR1S1PR3THRBITGB3ITGA2B | |
| SCHEMBL14302565 | 0.80 | THRB (0.46) | S1PR1S1PR3THRBCNR2ITGB3 | |
| SCHEMBL14907435 | 0.80 | S1PR1 (0.42) | S1PR1S1PR3RARBPTPN11THRB | |
| SCHEMBL13220826 | 0.80 | ITGB3 (0.49) | THRBITGB3ITGA2BTSHR | |
| SCHEMBL25500990 | 0.79 | THRB (0.50) | S1PR1S1PR3THRBHPGDTSHR | |
| SCHEMBL19722588 | 0.78 | S1PR1 (0.42) | S1PR1S1PR3RARBPTPN11ITGB3 | |
| SCHEMBL14088542 | 0.78 | FAAH (0.41) | THRBITGB3ITGA2BHPGDTSHR | |
| SCHEMBL19856065 | 0.78 | RARB (0.41) | S1PR1S1PR3RARBTHRBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771735-B1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-01-24 | — | — | EP | disclosed |
| US-9507185-B2 | Switch element comprising a liquid crystalline medium | MERCK PATENT GMBH (DE) | 2016-11-29 | — | — | US | disclosed |
| US-9507185-B2 | Switch element comprising a liquid crystalline medium | MERCK PATENT GMBH (DE) | 2016-11-29 | — | — | US | disclosed |
| US-20140293174-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| US-20140293174-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| WO-2013060406-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2013-05-02 | — | — | WO | disclosed |