Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17146872 | 0.99 | THRB (0.54) | THRBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL18826736 | 0.94 | MAPT (0.47) | THRBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL14907448 | 0.94 | THRB (0.56) | THRBMAPTSMN1; SMN2NPC1KMT2A | |
| SCHEMBL22451142 | 0.93 | THRB (0.57) | THRBMAPTSMN1; SMN2NPC1KMT2A | |
| SCHEMBL17364495 | 0.90 | THRB (0.53) | THRBMAPTSMN1; SMN2NPC1KMT2A | |
| SCHEMBL14000685 | 0.90 | THRB (0.53) | THRBMAPTSMN1; SMN2NPC1KMT2A | |
| SCHEMBL12534480 | 0.89 | MAPT (0.56) | THRBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL19621716 | 0.89 | THRB (0.57) | THRBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL24599286 | 0.88 | LMNA (0.50) | THRBMAPTSMN1; SMN2NPC1KMT2A | |
| SCHEMBL1072168 | 0.88 | THRB (0.51) | THRBMAPTSMN1; SMN2NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11248171-B2 | Polymerisable LC medium and polymer film with flat optical dispersion | MERCK PATENT GMBH (DE) | 2022-02-15 | — | — | US | disclosed |
| EP-3548586-B1 | POLYMERISABLE LC MEDIUM AND POLYMER FILM WITH FLAT OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2020-09-23 | — | — | EP | disclosed |
| US-10435628-B2 | Polymerisable LC medium and polymer film with negative optical dispersion | MERCK PATENT GMBH (DE) | 2019-10-08 | — | — | US | disclosed |
| WO-2018099883-A1 | POLYMERISABLE LC MEDIUM AND POLYMER FILM WITH FLAT OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2018-06-07 | — | — | WO | disclosed |
| US-20170226421-A1 | POLYMERISABLE LC MEDIUM AND POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2017-08-10 | — | — | US | disclosed |
| US-20170226421-A1 | POLYMERISABLE LC MEDIUM AND POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2017-08-10 | — | — | US | disclosed |
| WO-2016020035-A1 | POLYMERISABLE LC MEDIUM AND POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2016-02-11 | — | — | WO | disclosed |
| US-20120224245-A1 | POLYMERISABLE LC MATERIAL AND POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | Merck Patent Gesellschaft mit bescrankter Haftung (DE) | 2012-09-06 | — | — | US | disclosed |
| US-20120224245-A1 | POLYMERISABLE LC MATERIAL AND POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | Merck Patent Gesellschaft mit bescrankter Haftung (DE) | 2012-09-06 | — | — | US | disclosed |
| WO-2011050896-A1 | POLYMERISABLE LC MATERIAL AND POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2011-05-05 | — | — | WO | disclosed |