Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490852 | 0.81 | L3MBTL1 (0.57) | GAAKMT2AHSD17B10ALDH1A1ERN1 | |
| SCHEMBL8593124 | 0.79 | NPSR1 (0.69) | NPSR1GAAKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL13702338 | 0.75 | GAA (0.60) | NPSR1GAAKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL1490874 | 0.74 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL14507863 | 0.74 | ALDH1A1 (0.69) | NPSR1GAAKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL14355565 | 0.73 | NPSR1 (0.61) | NPSR1GAAKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL13753397 | 0.73 | NPSR1 (0.61) | NPSR1GAAKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL165801 | 0.73 | KDM4E (0.61) | NPSR1GAAKMT2AALDH1A1ERN1 | |
| SCHEMBL13753809 | 0.72 | NPSR1 (0.56) | NPSR1GAAKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL958217 | 0.71 | NPSR1 (0.59) | NPSR1GAAKMT2AHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897609-B2 | Aryl substituted imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-01 | — | — | US | disclosed |