Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13763531 | 0.82 | L3MBTL1 (0.80) | L3MBTL1SMN1; SMN2ALDH1A1POLBNPC1 | |
| SCHEMBL1490804 | 0.81 | NPSR1 (0.48) | SMN1; SMN2ALDH1A1KMT2AKDM4EERN1 | |
| SCHEMBL6358306 | 0.77 | ALDH1A1 (0.66) | L3MBTL1SMN1; SMN2ALDH1A1POLBNPC1 | |
| SCHEMBL5123030 | 0.76 | L3MBTL1 (0.71) | L3MBTL1SMN1; SMN2ALDH1A1POLBNPC1 | |
| SCHEMBL163436 | 0.76 | L3MBTL1 (0.71) | L3MBTL1SMN1; SMN2ALDH1A1POLBNPC1 | |
| SCHEMBL6027923 | 0.76 | L3MBTL1 (0.71) | L3MBTL1SMN1; SMN2ALDH1A1POLBNPC1 | |
| SCHEMBL2964483 | 0.75 | L3MBTL1 (0.69) | L3MBTL1SMN1; SMN2ALDH1A1POLBNPC1 | |
| SCHEMBL1490874 | 0.74 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1POLBHPGD | |
| SCHEMBL10790383 | 0.74 | L3MBTL1 (0.67) | L3MBTL1SMN1; SMN2ALDH1A1POLBNPC1 | |
| SCHEMBL1753828 | 0.73 | L3MBTL1 (0.71) | L3MBTL1SMN1; SMN2ALDH1A1POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897609-B2 | Aryl substituted imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-01 | — | — | US | disclosed |