SCHEMBL1490865

SCHEMBL1490865

[CH2]CC(NS(C)(=O)=O)c1cncc(CO)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.31
DYRK1A Q13627 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1491018 0.72 ADRB2 (0.42)
SCHEMBL5108969 0.68 CYP2A6 (0.41) CYP2A6DYRK1A
SCHEMBL28089087 0.66 KDM4E (0.42) CYP2A6
SCHEMBL17161760 0.65 PTGS2 (0.39) CYP2A6
SCHEMBL22774744 0.65 CYP2A6 (0.38) CYP2A6
SCHEMBL1490862 0.63 DYRK1A (0.33) CYP2A6DYRK1A
SCHEMBL2728918 0.62 CYP2A6 (0.47) CYP2A6DYRK1A
SCHEMBL21621638 0.62 CYP2A6 (0.36) CYP2A6DYRK1A
SCHEMBL26169682 0.62 CYP2A6 (0.36) CYP2A6
SCHEMBL1490864 0.61 POLB (0.32) CYP2A6DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7897609-B2 Aryl substituted imidazonaphthyridines 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-03-01 US disclosed