Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 2/20 | 0.39 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490877 | 0.73 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL1490865 | 0.72 | CYP2A6 (0.31) | — | |
| SCHEMBL1486713 | 0.71 | ADAMTS4 (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL27074457 | 0.70 | SLC6A2 (0.42) | L3MBTL1LMNASMN1; SMN2KDM4ECFTR | |
| SCHEMBL27425068 | 0.70 | NAPRT (0.44) | KCNA5L3MBTL1LMNASMN1; SMN2KDM4E | |
| SCHEMBL27608986 | 0.70 | SUCNR1 (0.53) | LMNAMAPK1 | |
| SCHEMBL7878877 | 0.69 | CFTR (0.57) | KCNA5L3MBTL1LMNASMN1; SMN2KDM4E | |
| SCHEMBL27703681 | 0.68 | CFTR (0.50) | ALDH1A1KCNA5L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL9046110 | 0.67 | CFTR (0.46) | KCNA5L3MBTL1LMNASMN1; SMN2KDM4E | |
| SCHEMBL7416466 | 0.67 | CFTR (0.46) | ALDH1A1KCNA5L3MBTL1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897609-B2 | Aryl substituted imidazonaphthyridines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-01 | — | — | US | disclosed |