Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27688228 | 0.84 | ALDH1A1 (0.33) | ALOX5APFEN1ALDH1A1MAPK1CYP2A6 | |
| SCHEMBL150097 | 0.83 | PTGS2 (0.35) | — | |
| SCHEMBL4319544 | 0.83 | — | — | |
| SCHEMBL435280 | 0.80 | AHR (0.35) | CYP2A6AHR | |
| SCHEMBL29019397 | 0.80 | PTGS2 (0.40) | MEN1KMT2A | |
| SCHEMBL15286357 | 0.80 | — | — | |
| SCHEMBL29018084 | 0.79 | ALDH1A1 (0.36) | ALDH1A1MAPK1CYP2A6MEN1KMT2A | |
| SCHEMBL693886 | 0.79 | MEN1 (0.35) | ALDH1A1MAPK1CYP2A6MEN1KMT2A | |
| SCHEMBL2886283 | 0.78 | — | — | |
| SCHEMBL29246765 | 0.78 | PTGS1 (0.34) | ALDH1A1MAPK1CYP2A6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-B1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2009-12-09 | — | — | EP | claimed |
| CN-104350059-B | There is the thiazolopyridin ketone of weeding and insecticidal activity | 拜耳知识产权有限责任公司 | 2016-12-07 | — | — | CN | disclosed |
| US-9307767-B2 | Herbicidally and insecticidally active thiazolopyridinones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-12 | — | — | US | disclosed |
| EP-2831084-B1 | HERBICIDAL AND INSECTICIDAL THIAZOLOPYRIDINONES | BAYER IP GMBH (DE) | 2016-03-23 | — | — | EP | disclosed |
| US-20150045217-A1 | Herbicidally and Insecticidally Active Thiazolopyridinones | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2015-02-12 | — | — | US | disclosed |
| CN-104350059-A | Herbicidally and insecticidally active thiazolopyridinones | BAYER IP GMBH | 2015-02-11 | — | — | CN | disclosed |
| EP-2831084-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE THIAZOLOPYRIDINONES | Bayer Intellectual Property GmbH (DE) | 2015-02-04 | — | — | EP | disclosed |
| WO-2013144096-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE THIAZOLOPYRIDINONES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-03 | — | — | WO | disclosed |
| EP-2477982-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | Calcimedica, Inc. (US) | 2012-07-25 | — | — | EP | disclosed |
| WO-2011034962-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045217-A1 | Herbicidally and Insecticidally Active Thiazolopyridinones | CBR3, DDT, CBR1 | ALOX5AP 3918/4885FEN1 1635/4885ALDH1A1 339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.