Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150097 | 0.83 | PTGS2 (0.35) | PTGS2PTGS1RPS6KA3NPC1RAB9A | |
| SCHEMBL4319544 | 0.83 | — | — | |
| SCHEMBL435280 | 0.80 | AHR (0.35) | PTGS2PTGS1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1491045 | 0.80 | ALOX5AP (0.33) | MEN1KMT2A | |
| SCHEMBL15286357 | 0.80 | — | — | |
| SCHEMBL29019414 | 0.79 | AKR1C3 (0.43) | PTGS2PTGS1PDE3BPDE3A | |
| SCHEMBL20703486 | 0.79 | AKR1C3 (0.42) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL8074245 | 0.79 | TAAR1 (0.35) | NPC1RAB9AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL3544339 | 0.79 | ACHE (0.35) | PTGS2PTGS1ACHEMEN1NPC1 | |
| SCHEMBL693886 | 0.79 | MEN1 (0.35) | PTGS2PTGS1RPS6KA3MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003123-B | Modulators of the PGI2 receptor for the treatment of prostacyclin (PGI 2) receptor related disorders | 艾尼纳制药公司 | 2023-06-23 | — | — | CN | disclosed |