Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGAV | P06756 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 10/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1547894 | 0.78 | CES2 (0.36) | IDO1MAPTRAPGEF4LMNARAB9A | |
| SCHEMBL1547878 | 0.78 | HTR3E (0.52) | ITGB3ITGAVIDO1KMT2AALDH1A1 | |
| SCHEMBL13131511 | 0.77 | IDO1 (0.50) | ITGB3ITGAVIDO1TDO2MEN1 | |
| SCHEMBL17616922 | 0.72 | KMT2A (0.71) | ITGB3ITGAVIDO1EGFRTDO2 | |
| SCHEMBL17341862 | 0.72 | KMT2A (0.71) | ITGB3ITGAVIDO1EGFRTDO2 | |
| SCHEMBL30298592 | 0.72 | ITGB3 (0.46) | ITGB3ITGAVIDO1EGFRTDO2 | |
| SCHEMBL1018986 | 0.72 | ITGB3 (0.46) | ITGB3ITGAVIDO1EGFRTDO2 | |
| SCHEMBL15740371 | 0.72 | ITGB3 (0.46) | ITGB3ITGAVIDO1EGFRTDO2 | |
| SCHEMBL29454784 | 0.72 | MAPK1 (0.68) | ITGB3ITGAVIDO1EGFRTDO2 | |
| SCHEMBL334925 | 0.72 | MAPK1 (0.68) | ITGB3ITGAVIDO1EGFRTDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011029832-A1 | NOVEL THIAZOL AND OXAZOL HEPCIDINE ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2011-03-17 | — | — | WO | disclosed |