Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | IDO1 | P14902 | 7/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29454784 | 1.00 | MAPK1 (0.68) | MAPK1TDP1IDO1ITGB3ITGAV | |
| SCHEMBL8676888 | 0.87 | MAPK1 (0.53) | MAPK1TDP1IDO1ITGB3ITGAV | |
| SCHEMBL3831454 | 0.84 | MAPK1 (0.68) | MAPK1TDP1IDO1ITGB3ITGAV | |
| SCHEMBL8093598 | 0.82 | CYP3A4 (0.50) | MAPK1TDP1IDO1ITGB3ITGAV | |
| SCHEMBL161540 | 0.81 | MAPK1 (0.52) | MAPK1TDP1IDO1CYP3A4TRPA1 | |
| SCHEMBL29824353 | 0.81 | MAPK1 (0.52) | MAPK1TDP1IDO1CYP3A4TRPA1 | |
| SCHEMBL58874 | 0.81 | MAPK1 (1.00) | MAPK1TDP1ITGB3ITGAVCYP3A4 | |
| SCHEMBL29376406 | 0.81 | MAPK1 (1.00) | MAPK1TDP1ITGB3ITGAVCYP3A4 | |
| SCHEMBL418944 | 0.80 | CYP3A4 (0.58) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL1018986 | 0.80 | ITGB3 (0.46) | MAPK1TDP1IDO1ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 496 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12528777-B2 | Quinazolinones derivatives for treatment of non-alcoholic fatty liver disease, preparation and use thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2026-01-20 | — | — | US | claimed |
| CN-119431706-A | Fatigue-resistant polyurethane elastomer and preparation method and application thereof | 万勋科技(深圳)有限公司 | 2025-02-14 | — | — | CN | claimed |
| US-20230357165-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-11-09 | — | — | US | claimed |
| EP-4171569-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | Council of Scientific & Industrial Research (IN) | 2023-05-03 | — | — | EP | claimed |
| WO-2022003712-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-01-06 | — | — | WO | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| US-12528777-B2 | Quinazolinones derivatives for treatment of non-alcoholic fatty liver disease, preparation and use thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2026-01-20 | — | — | US | disclosed |
| US-20250235462-A1 | NOVEL CAPSID ASSEMBLY INHIBITORS | AM SCIENCES INC (KR) | 2025-07-24 | — | — | US | disclosed |
| CN-119431706-A | Fatigue-resistant polyurethane elastomer and preparation method and application thereof | 万勋科技(深圳)有限公司 | 2025-02-14 | — | — | CN | disclosed |
| US-20250009742-A1 | NOVEL CAPSID ASSEMBLY INHIBITORS | META-IMMUNE, INC. (KR) | 2025-01-09 | — | — | US | disclosed |
| CN-113923988-B | Substituted arylmethyl ureas and heteroarylmethyl ureas, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2024-12-13 | — | — | CN | disclosed |
| EP-4416142-A1 | NOVEL CAPSID ASSEMBLY INHIBITORS | AM Sciences Inc (KR) | 2024-08-21 | — | — | EP | disclosed |
| EP-4416150-A1 | NOVEL CAPSID ASSEMBLY INHIBITORS | AM Sciences Inc (KR) | 2024-08-21 | — | — | EP | disclosed |
| EP-0156091-A1 | Beta-oxo-alpha-carbamoyl-pyrrolepropionitriles, processes for their preparation, pharmaceutical compositions comprising these compounds and their therapeutic use | CIBA-GEIGY AG (CH) | 1985-10-02 | — | — | EP | disclosed |
| EP-0153127-A2 | N-aryl-3-aryl-4,5-dihydro-1H-pyrazole-1-carboxamides, processes for their production, insecticidal compositions containing them and methods for combatting insects | ROHM AND HAAS COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| US-4470930-A | Preparation of nuclear chlorinated aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-09-11 | — | — | US | disclosed |
| US-4207317-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-06-10 | — | — | US | disclosed |
| US-4131751-A | PHENYLENE, PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1978-12-26 | — | — | US | disclosed |
| US-4046909-A | Pyrrolidylidene, piperidylidene and hexahydroazepinylidene ureas as CNS depressants | MCNEIL LABORATORIES, INCORPORATED (US) | 1977-09-06 | — | — | US | disclosed |
| US-3998958-A | Pyrrolidylidene, piperidylidene and hexahydroazepinylidene ureas as CNS depressants | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250235462-A1 | NOVEL CAPSID ASSEMBLY INHIBITORS | ZC3HAV1, GTF3C3, ZC3HAV1L | MAPK1 2616/4885TDP1 1201/4885IDO1 2952/4885 |
| US-20230357165-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | ATG7, GOT1, LIPC | MAPK1 2282/4885TDP1 985/4885IDO1 2054/4885 |
| US-12528777-B2 | Quinazolinones derivatives for treatment of non-alcoholic fatty liver disease, preparation and use thereof | ATG7, GOT1, ULK1 | MAPK1 2409/4885TDP1 1533/4885IDO1 2796/4885 |
| US-20250009742-A1 | NOVEL CAPSID ASSEMBLY INHIBITORS | ZC3HAV1, ZC3HAV1L, MAVS | MAPK1 2676/4885TDP1 1195/4885IDO1 3056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.