Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | MAP2K3 | P46734 | 2/20 | 0.45 |
| ▸ | CDC7 | O00311 | 5/20 | 0.44 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 4/20 | 0.40 |
| ▸ | CDK8 | P49336 | 4/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 2/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.37 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14917460 | 0.86 | MEN1 (0.47) | SRCKDRBRAFMAP2K3CDC7 | |
| SCHEMBL14917433 | 0.81 | MKNK1 (0.50) | CHEK2MKNK1MKNK2IKBKB | |
| SCHEMBL16713264 | 0.79 | HSP90AA1 (0.36) | SRCKDRBRAFMAP2K3CDC7 | |
| SCHEMBL19138009 | 0.74 | HTT (0.46) | — | |
| SCHEMBL15380562 | 0.74 | MKNK1 (0.44) | CDC7CHEK2MKNK1MKNK2 | |
| SCHEMBL17555856 | 0.74 | MAPT (0.42) | PDE3BPDE3ACASP1 | |
| SCHEMBL14917440 | 0.72 | CHEK2 (0.49) | SRCKDRBRAFMAP2K3CDC7 | |
| SCHEMBL27779234 | 0.72 | CDK5 (0.50) | KDRCDK8 | |
| SCHEMBL14917445 | 0.72 | PIM1 (0.52) | SRCMKNK2IKBKB | |
| SCHEMBL4976686 | 0.72 | CYP17A1 (0.46) | SRCKDRBRAFMAP2K3CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130116430-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116430-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | SYK, CD38, BTK | SRC 73/4885KDR 403/4885BRAF 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.