Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491946 | 0.84 | FGF2 (0.44) | LGALS8ALDH1A1CYP3A4HPGDLMNA | |
| SCHEMBL1491902 | 0.81 | MMP1 (0.34) | LGALS8ALDH1A1CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL4189072 | 0.75 | CYP3A4 (0.49) | LGALS8ALDH1A1CYP3A4LMNATP53 | |
| SCHEMBL1491947 | 0.74 | CA12 (0.51) | ALDH1A1NR1H3HPGDKDM4ENPC1 | |
| SCHEMBL1491881 | 0.74 | CA12 (0.51) | ALDH1A1NR1H3HPGDKDM4ENPC1 | |
| SCHEMBL1491923 | 0.73 | FGF2 (0.43) | LGALS8ALDH1A1CYP3A4LMNANPC1 | |
| SCHEMBL7957798 | 0.72 | ALDH1A1 (0.43) | LGALS8ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL1491891 | 0.70 | CYP3A4 (0.41) | LGALS8ALDH1A1CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL23121475 | 0.70 | LGALS8 (0.50) | LGALS8CYP3A4NPC1TP53RAB9A | |
| SCHEMBL13755879 | 0.69 | CYP3A4 (0.54) | ALDH1A1CYP3A4LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7901687-B2 | Antibodies for the detection of Bacillus anthracis and vaccine against B. anthracis infections | ETH ZURICH (CH) | 2011-03-08 | — | — | US | disclosed |
| US-20090155299-A1 | Antibodies for the Detection of Bacillus Anthracis and Vaccine Against B. Anthracis Infections | SCHWEIZERISCHES TROPENINSTITUT (CH) | 2009-06-18 | — | — | US | disclosed |
| EP-2012821-A2 | ANTIBODIES FOR THE DETECTION OF BACILLUS ANTHRACIS AND VACCINE AGAINST B. ANTHRACIS INFECTIONS | ETH Zürich (CH) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007125089-A2 | ANTIBODIES FOR THE DETECTION OF BACILLUS ANTHRACIS AND VACCINE AGAINST B. ANTHRACIS INFECTIONS | ETH Zürich (CH) | 2007-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155299-A1 | Antibodies for the Detection of Bacillus Anthracis and Vaccine Against B. Anthracis Infections | ANTXR2, CERT1, DAD1 | LGALS8 1200/4885ALDH1A1 2915/4885NR1H3 2160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.