Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14918445 | 0.94 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| SCHEMBL14918279 | 0.93 | HDAC3 (0.53) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| SCHEMBL14918977 | 0.92 | HDAC1 (0.55) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| SCHEMBL14918978 | 0.92 | HDAC1 (0.55) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| SCHEMBL14918218 | 0.92 | HDAC1 (0.55) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| SCHEMBL14918797 | 0.85 | LMNA (0.53) | ALDH1A1LMNATSHRGAAL3MBTL1 | |
| SCHEMBL14918585 | 0.82 | HDAC1 (0.55) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| SCHEMBL14918961 | 0.82 | PDK1 (0.47) | ALDH1A1LMNAHSD17B10TSHRL3MBTL1 | |
| SCHEMBL14918950 | 0.81 | MAPT (0.58) | LMNAGAAALOX15L3MBTL1HPGD | |
| SCHEMBL14918925 | 0.80 | MAPT (0.59) | ALDH1A1LMNAL3MBTL1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066836-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | claimed |
| WO-2013066836-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |