Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 6/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14917737 | 0.92 | DPP4 (0.30) | DPP4 | |
| SCHEMBL16011161 | 0.90 | TIPARP (0.31) | GPR6TIPARP | |
| SCHEMBL14918457 | 0.89 | TMPRSS15 (0.32) | GPR6DPP4 | |
| SCHEMBL16010869 | 0.87 | MAPT (0.35) | GPR6DPP4TIPARP | |
| SCHEMBL14917851 | 0.87 | MAPT (0.35) | GPR6DPP4TIPARP | |
| SCHEMBL16011125 | 0.86 | GPR119 (0.43) | GPR6GPR119DPP4TIPARP | |
| SCHEMBL16011266 | 0.85 | RAB9A (0.35) | GPR6DPP4 | |
| SCHEMBL16011001 | 0.85 | GPR119 (0.39) | GPR6GPR119 | |
| SCHEMBL16011004 | 0.85 | GPR119 (0.39) | GPR6GPR119 | |
| SCHEMBL14932744 | 0.85 | GPR119 (0.39) | GPR6GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256756-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA, INC. | 2014-09-11 | — | — | US | disclosed |
| WO-2013066869-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA INC. (US) | 2013-05-10 | — | — | WO | disclosed |
| US-8329838-B2 | Norbornene-type polymers, compositions thereof and lithographic processes using such compositions | PROMERUS LLC (US) | 2012-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256756-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | GPR119, GPR139, GLP1R | GPR6 20/4885GPR119 1/4885DPP4 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.