Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | SLC40A1 | Q9NP59 | 10/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30854823 | 0.86 | SLC40A1 (0.70) | MEN1KMT2ASLC40A1ATMGAA | |
| SCHEMBL29255663 | 0.86 | SLC40A1 (0.70) | MEN1KMT2ASLC40A1ATMGAA | |
| SCHEMBL13633871 | 0.84 | MCL1 (0.65) | MEN1KMT2ASLC40A1ATMMCL1 | |
| SCHEMBL30925515 | 0.82 | SLC40A1 (1.00) | MEN1KMT2ASLC40A1 | |
| SCHEMBL11973322 | 0.82 | SLC40A1 (1.00) | MEN1KMT2ASLC40A1 | |
| SCHEMBL8337625 | 0.81 | MEN1 (0.62) | MEN1KMT2ASLC40A1ATMGAA | |
| SCHEMBL1507919 | 0.81 | SLC40A1 (0.76) | MEN1KMT2ASLC40A1ATMGAA | |
| SCHEMBL30854809 | 0.81 | SLC40A1 (0.76) | MEN1KMT2ASLC40A1ATMGAA | |
| SCHEMBL22315265 | 0.80 | ATM (0.74) | MEN1KMT2ASLC40A1ATMGAA | |
| SCHEMBL9930754 | 0.79 | CCR2 (0.66) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066469-A2 | KINASE INHIBITORS CAPABLE OF INCREASING THE SENSITIVITY OF BACTERIAL PATHOGENS TO B-LACTAM ANTIBIOTICS | SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) | 2013-05-10 | — | — | WO | disclosed |