SCHEMBL30854823

SCHEMBL30854823

O=S(=O)(Nc1cc(Cl)cc2cccnc12)c1cccc2cccnc12

nearest known ligand 0.70

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC40A1 Q9NP59 12/20 0.70
MEN1 O00255 6/20 0.67
KMT2A Q03164 6/20 0.67
ATM Q13315 1/20 0.65
GAA P10253 1/20 0.61
TDP1 Q9NUW8 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29255663 1.00 SLC40A1 (0.70) SLC40A1MEN1KMT2AATMGAA
SCHEMBL14919762 0.86 MEN1 (0.73) SLC40A1MEN1KMT2AATMGAA
SCHEMBL29255666 0.85 SLC40A1 (0.72) SLC40A1MEN1KMT2AATMGAA
SCHEMBL30854811 0.85 SLC40A1 (0.72) SLC40A1MEN1KMT2AATMGAA
SCHEMBL1507919 0.84 SLC40A1 (0.76) SLC40A1MEN1KMT2AATMGAA
SCHEMBL30854809 0.84 SLC40A1 (0.76) SLC40A1MEN1KMT2AATMGAA
SCHEMBL11973412 0.83 SLC40A1 (1.00) SLC40A1MEN1KMT2AATMTDP1
SCHEMBL29255671 0.81 CXCR2 (0.77) SLC40A1MEN1KMT2ATDP1
SCHEMBL30854819 0.81 CXCR2 (0.77) SLC40A1MEN1KMT2ATDP1
SCHEMBL29255668 0.79 SLC40A1 (0.68) SLC40A1MEN1KMT2AATMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117865886-B N- (quinoline-8-yl) quinoline-8-sulfonamide compound and application thereof 中国药科大学 2024-05-10 CN disclosed
CN-117865886-A N- (quinoline-8-yl) quinoline-8-sulfonamide compound and application thereof 中国药科大学 2024-04-12 CN disclosed