Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL422055 | 0.74 | ALDH3A1 (0.77) | GAAHTTTSHRALDH1A1USP2 | |
| SCHEMBL11610961 | 0.73 | GAA (1.00) | GAAHTTTSHRALDH1A1USP2 | |
| SCHEMBL1804076 | 0.73 | HTT (0.66) | GAAHTTTSHRALDH1A1USP2 | |
| SCHEMBL1248579 | 0.73 | HTR6 (0.53) | TSHRALDH1A1LMNA | |
| SCHEMBL1249603 | 0.73 | HTR6 (0.57) | HTT | |
| SCHEMBL8327245 | 0.71 | HTT (0.80) | GAAHTTTSHRALDH1A1USP2 | |
| SCHEMBL22462430 | 0.71 | ALDH3A1 (0.61) | GAAHTTTSHRALDH1A1USP2 | |
| SCHEMBL1070947 | 0.71 | ALDH3A1 (0.57) | GAAHTTTSHRALDH1A1USP2 | |
| SCHEMBL7100805 | 0.71 | ALDH3A1 (0.61) | GAAHTTTSHRALDH1A1USP2 | |
| SCHEMBL830432 | 0.71 | ALDH3A1 (0.57) | GAAHTTTSHRALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066469-A2 | KINASE INHIBITORS CAPABLE OF INCREASING THE SENSITIVITY OF BACTERIAL PATHOGENS TO B-LACTAM ANTIBIOTICS | SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) | 2013-05-10 | — | — | WO | disclosed |