SCHEMBL14920004

SCHEMBL14920004

O=S1(=O)C(c2c(Cl)cc(Cl)nc2Cl)=C(O)c2ncccc2N1CC(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL442604 0.85 P2RX7 (0.31)
SCHEMBL409942 0.74 SLC6A7 (0.33)
SCHEMBL2373539 0.73 RBP4 (0.37)
SCHEMBL2373398 0.71 BRAF (0.36)
SCHEMBL2597742 0.68 HRH1 (0.32)
SCHEMBL272460 0.66
SCHEMBL438893 0.65 DPP4 (0.33)
SCHEMBL12296769 0.65 KCNN4 (0.34)
SCHEMBL410925 0.60 TACR1 (0.34)
SCHEMBL442286 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10801035-B2 Plants having increased tolerance to herbicides BASF SE (DE) 2020-10-13 US claimed
US-10801035-B2 Plants having increased tolerance to herbicides BASF SE (DE) 2020-10-13 US disclosed
US-10294488-B2 Herbicide-metabolizing cytochrome P450 monooxygenases BASF SE (DE) 2019-05-21 US disclosed
US-20150322453-A1 HERBICIDE-METABOLIZING CYTOCHROME P450 MONOOXYGENASES BASF SE (DE) 2015-11-12 US disclosed
US-20150005168-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF SE (DE) 2015-01-01 US disclosed
EP-2773763-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF SE (DE) 2014-09-10 EP disclosed
WO-2014097085-A1 HERBICIDE-METABOLIZING CYTOCHROME P450 MONOOXYGENASES BASF SE (DE) 2014-06-26 WO disclosed
WO-2013064987-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF SE (DE) 2013-05-10 WO disclosed