Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14919923 | 0.76 | PLAU (0.36) | HTTPLAU | |
| SCHEMBL14919965 | 0.75 | — | — | |
| SCHEMBL26121235 | 0.73 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1TRPM8GAAHTT | |
| SCHEMBL31338960 | 0.73 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1TRPM8GAAHTT | |
| SCHEMBL14920148 | 0.73 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1GAAHTTPOLB | |
| SCHEMBL14920531 | 0.73 | KMT2A (0.43) | L3MBTL1ALDH1A1GAAHTTPOLB | |
| SCHEMBL14920319 | 0.73 | ALDH1A1 (0.42) | L3MBTL1ALDH1A1GAAHTTPOLB | |
| SCHEMBL14920987 | 0.73 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1GAAHTTPOLB | |
| SCHEMBL14920448 | 0.72 | ALDH1A1 (0.44) | ALDH1A1GAAHTTPOLBKDM4E | |
| SCHEMBL14920146 | 0.71 | ALDH1A1 (0.50) | ALDH1A1GAAHTTPLAUSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773617-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-22 | — | — | EP | disclosed |
| US-20160309717-A1 | Compounds with Nematicidal Activity | BAYER CROPSCIENCE AG (DE) | 2016-10-27 | — | — | US | disclosed |
| US-20160309717-A1 | Compounds with Nematicidal Activity | BAYER CROPSCIENCE AG (DE) | 2016-10-27 | — | — | US | disclosed |
| US-20160309717-A1 | Compounds with Nematicidal Activity | BAYER CROPSCIENCE AG (DE) | 2016-10-27 | — | — | US | disclosed |
| EP-3083585-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | Bayer CropScience Aktiengesellschaft (DE) | 2016-10-26 | — | — | EP | disclosed |
| US-20150223456-A1 | PESTICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2015-08-13 | — | — | US | disclosed |
| US-20150223456-A1 | PESTICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2015-08-13 | — | — | US | disclosed |
| US-20150223456-A1 | PESTICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2015-08-13 | — | — | US | disclosed |
| WO-2015091424-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2015-06-25 | — | — | WO | disclosed |
| WO-2015091424-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2015-06-25 | — | — | WO | disclosed |
| US-9040708-B2 | Pesticidal compounds | SYNGENTA LIMITED (GB) | 2015-05-26 | — | — | US | disclosed |
| US-9040708-B2 | Pesticidal compounds | SYNGENTA LIMITED (GB) | 2015-05-26 | — | — | US | disclosed |
| US-9040708-B2 | Pesticidal compounds | SYNGENTA LIMITED (GB) | 2015-05-26 | — | — | US | disclosed |
| US-20140296067-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | US | disclosed |
| US-20140296067-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | US | disclosed |
| US-20140296067-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | US | disclosed |
| EP-2773617-A1 | PESTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013064521-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160309717-A1 | Compounds with Nematicidal Activity | ACHE, NAAA, TUBA3C | L3MBTL1 1028/4885ALDH1A1 2731/4885TRPM8 918/4885 |
| US-20150223456-A1 | PESTICIDAL COMPOUNDS | C5, CBR3, C3AR1 | L3MBTL1 289/4885ALDH1A1 1233/4885TRPM8 3406/4885 |
| US-20140296067-A1 | PESTICIDAL COMPOUNDS | C5, CBR3, C3AR1 | L3MBTL1 289/4885ALDH1A1 1233/4885TRPM8 3406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.