Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14920148 | 0.75 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2KMT2AKDM4EPOLB | |
| SCHEMBL3370446 | 0.73 | KMT2A (0.58) | ALDH1A1SMN1; SMN2KMT2AKDM4EPOLB | |
| SCHEMBL14920536 | 0.73 | P2RX7 (0.55) | ALDH1A1SMN1; SMN2KMT2AKDM4EPOLB | |
| SCHEMBL4428168 | 0.72 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2KMT2AKDM4EPOLB | |
| SCHEMBL14920146 | 0.72 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KMT2APLAUGAA | |
| SCHEMBL14920531 | 0.72 | KMT2A (0.43) | ALDH1A1SMN1; SMN2KMT2AKDM4EPOLB | |
| SCHEMBL14920319 | 0.72 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KMT2AKDM4EPOLB | |
| SCHEMBL14920299 | 0.72 | L3MBTL1 (0.43) | ALDH1A1SMN1; SMN2KDM4EPOLBPLAU | |
| SCHEMBL14920987 | 0.72 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KMT2AKDM4EPOLB | |
| SCHEMBL14920646 | 0.71 | KMT2A (0.56) | ALDH1A1SMN1; SMN2KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773617-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-22 | — | — | EP | disclosed |
| US-20150223456-A1 | PESTICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2015-08-13 | — | — | US | disclosed |
| US-20150223456-A1 | PESTICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2015-08-13 | — | — | US | disclosed |
| US-20150223456-A1 | PESTICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2015-08-13 | — | — | US | disclosed |
| US-9040708-B2 | Pesticidal compounds | SYNGENTA LIMITED (GB) | 2015-05-26 | — | — | US | disclosed |
| US-9040708-B2 | Pesticidal compounds | SYNGENTA LIMITED (GB) | 2015-05-26 | — | — | US | disclosed |
| US-9040708-B2 | Pesticidal compounds | SYNGENTA LIMITED (GB) | 2015-05-26 | — | — | US | disclosed |
| US-20140296067-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | US | disclosed |
| US-20140296067-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | US | disclosed |
| US-20140296067-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | US | disclosed |
| EP-2773617-A1 | PESTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013064521-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-05-10 | — | — | WO | disclosed |
| WO-2013064521-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150223456-A1 | PESTICIDAL COMPOUNDS | C5, CBR3, C3AR1 | ALDH1A1 1233/4885SMN1; SMN2 4296/4885KMT2A 4358/4885 |
| US-20140296067-A1 | PESTICIDAL COMPOUNDS | C5, CBR3, C3AR1 | ALDH1A1 1233/4885SMN1; SMN2 4296/4885KMT2A 4358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.