Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | TKT | P29401 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952737 | 0.85 | LOXL2 (0.38) | TRPV1TKTP2RX7LOXL2KDM4E | |
| SCHEMBL27604070 | 0.82 | TRPV1 (0.34) | TRPV1TKTL3MBTL1FABP4 | |
| SCHEMBL10278275 | 0.82 | TAAR1 (0.37) | TAAR1HTR2AHTR2CCYP1A2 | |
| SCHEMBL4485875 | 0.79 | KMT2A (0.39) | TRPV1TKTP2RX7KDM4EALDH1A1 | |
| SCHEMBL30910910 | 0.79 | KMT2A (0.39) | TRPV1TKTP2RX7KDM4EALDH1A1 | |
| SCHEMBL29464837 | 0.78 | TRPV1 (0.37) | TRPV1TKTP2RX7KDM4EALDH1A1 | |
| SCHEMBL12266190 | 0.78 | TRPV1 (0.40) | TRPV1P2RX7ALDH1A1L3MBTL1 | |
| SCHEMBL1742466 | 0.78 | TRPV1 (0.37) | TRPV1TKTP2RX7KDM4EALDH1A1 | |
| SCHEMBL5036133 | 0.78 | TRPV1 (0.37) | TRPV1P2RX7KDM4EALDH1A1HSD17B10 | |
| SCHEMBL2129756 | 0.75 | MBOAT4 (0.49) | TAAR1TRPV1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9301526-B2 | Compounds with nematicidal activity | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-05 | — | — | US | disclosed |
| US-9301526-B2 | Compounds with nematicidal activity | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-05 | — | — | US | disclosed |
| US-20140256728-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-11 | — | — | US | disclosed |
| US-20140256728-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-11 | — | — | US | disclosed |
| US-20140256728-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-11 | — | — | US | disclosed |
| EP-2773215-A2 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | Bayer Intellectual Property GmbH (DE) | 2014-09-10 | — | — | EP | disclosed |
| EP-2773203-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | Bayer Intellectual Property GmbH (DE) | 2014-09-10 | — | — | EP | disclosed |
| US-20140249149-A1 | Compounds with Nematicidal Activity | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-04 | — | — | US | disclosed |
| US-20140249149-A1 | Compounds with Nematicidal Activity | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-09-04 | — | — | US | disclosed |
| WO-2013064461-A2 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |
| WO-2013064460-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |
| WO-2013064460-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |
| WO-2013064461-A2 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256728-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | ACHE, TUBA3C, NAAA | TAAR1 3660/4885TRPV1 191/4885TKT 2154/4885 |
| US-20140249149-A1 | Compounds with Nematicidal Activity | ACHE, NAAA, TUBA3C | TAAR1 3582/4885TRPV1 144/4885TKT 2430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.