Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 7/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14922591 | 0.92 | SMN1; SMN2 (0.36) | FPR2FFAR4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12197225 | 0.91 | FFAR4 (0.33) | FPR2FFAR4SMN1; SMN2SSTR5FGFR1 | |
| SCHEMBL12224025 | 0.91 | FPR2 (0.33) | FPR2FFAR4SMN1; SMN2SSTR5FGFR1 | |
| SCHEMBL12197347 | 0.91 | FFAR4 (0.33) | FPR2FFAR4SMN1; SMN2SSTR5FGFR1 | |
| SCHEMBL12224042 | 0.88 | SSTR5 (0.32) | FPR2FFAR4SMN1; SMN2SSTR5 | |
| SCHEMBL14922667 | 0.87 | SCN9A (0.37) | FPR2SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL14922607 | 0.87 | SCN9A (0.37) | FPR2SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL14922689 | 0.86 | SMN1; SMN2 (0.36) | FFAR4SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL14922680 | 0.86 | SMN1; SMN2 (0.36) | FFAR4SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL14922599 | 0.86 | SMN1; SMN2 (0.39) | FPR2SMN1; SMN2SSTR5FGFR1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435422-B2 | Five-ring compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |