SCHEMBL14922771

SCHEMBL14922771

Cc1cccc(N=C2c3ccccc3-c3ccccc32)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
MAPT P10636 3/20 0.54
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
HTR3E A5X5Y0 2/20 0.46
HTR3B O95264 2/20 0.46
HTR3A P46098 2/20 0.46
HTR3D Q70Z44 2/20 0.46
HTR3C Q8WXA8 2/20 0.46
HSP90AA1 P07900 1/20 0.45
ACHE P22303 1/20 0.42
NPC1 O15118 1/20 0.41
NSD2 O96028 1/20 0.41
CASP3 P42574 1/20 0.41
RAB9A P51151 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12111757 0.83 ALDH1A1 (0.60) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL14922772 0.79 MAPT (0.43) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL14922784 0.78 HSP90AA1 (0.65) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL28417579 0.77 ALDH1A1 (0.77) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL4402246 0.76 ALDH1A1 (0.50) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL14922779 0.76 MEN1 (0.41) ALDH1A1MAPTMEN1KMT2AHTR3E
SCHEMBL9510943 0.75 ALDH1A1 (0.84) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL18134597 0.73 ALDH1A1 (1.00) ALDH1A1MEN1KMT2A
SCHEMBL14806769 0.73 ALDH1A1 (0.79) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL30965324 0.72 HTR3E (0.50) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8465889-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2013-06-18 US disclosed
US-8435706-B2 2013-05-07 US disclosed