SCHEMBL14922772

SCHEMBL14922772

Cc1ccc(-c2cccc3c2-c2c(cccc2-c2ccc(C)cc2)C3=Nc2cccc(C)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.43
HSP90AA1 P07900 1/20 0.42
HTR3E A5X5Y0 2/20 0.39
HTR3B O95264 2/20 0.39
HTR3A P46098 2/20 0.39
HTR3D Q70Z44 2/20 0.39
HTR3C Q8WXA8 2/20 0.39
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
ALDH1A1 P00352 3/20 0.36
POLB P06746 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
NPC1 O15118 1/20 0.35
NSD2 O96028 1/20 0.35
CASP3 P42574 1/20 0.35
RAB9A P51151 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14922779 0.89 MEN1 (0.41) MAPTHSP90AA1HTR3EHTR3BHTR3A
SCHEMBL12111789 0.89 POLB (0.37) MAPTHSP90AA1MEN1KMT2AALDH1A1
SCHEMBL14922771 0.79 ALDH1A1 (0.56) MAPTHSP90AA1HTR3EHTR3BHTR3A
SCHEMBL12111787 0.79 ALDH1A1 (0.38) MAPTHSP90AA1ALDH1A1CA1CA2
SCHEMBL12111788 0.78 AGTR1 (0.39) MAPTMEN1KMT2AALDH1A1HTT
SCHEMBL12111799 0.75 GALR3 (0.38) MAPTNPC1RAB9ACYP3A4CYP2C19
SCHEMBL14922784 0.70 HSP90AA1 (0.65) MAPTHSP90AA1MEN1KMT2AALDH1A1
SCHEMBL12111802 0.69 POLB (0.40) MAPTHSP90AA1HTR3EHTR3BHTR3A
SCHEMBL14922774 0.67 ELANE (0.47) MAPTMEN1KMT2AALDH1A1POLB
SCHEMBL10814151 0.65 NPC1 (0.69) MAPTHSP90AA1HTR3EHTR3BHTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8465889-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2013-06-18 US disclosed
US-8435706-B2 2013-05-07 US disclosed