Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.65 |
| ▸ | S100A4 | P26447 | 2/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12111804 | 0.91 | HSP90AA1 (0.54) | HSP90AA1S100A4PTPRCKMT2AMEN1 | |
| SCHEMBL7733450 | 0.80 | HSP90AA1 (0.52) | HSP90AA1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL14922778 | 0.79 | HSP90AA1 (1.00) | HSP90AA1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL11781232 | 0.78 | HSP90AA1 (0.64) | HSP90AA1S100A4PTPRCKMT2AMEN1 | |
| SCHEMBL11781236 | 0.78 | HSP90AA1 (0.64) | HSP90AA1S100A4PTPRCKMT2AMEN1 | |
| SCHEMBL14922771 | 0.78 | ALDH1A1 (0.56) | HSP90AA1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL16601699 | 0.75 | S100A4 (0.48) | HSP90AA1S100A4PTPRCKMT2AMEN1 | |
| SCHEMBL1559811 | 0.71 | S100A4 (0.75) | S100A4PTPRCKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11780487 | 0.70 | HSP90AA1 (0.57) | HSP90AA1S100A4PTPRCKMT2AMEN1 | |
| SCHEMBL11780494 | 0.70 | HSP90AA1 (0.57) | HSP90AA1S100A4PTPRCKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8465889-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2013-06-18 | — | — | US | disclosed |
| US-8435706-B2 | — | — | 2013-05-07 | — | — | US | disclosed |