SCHEMBL14922948

SCHEMBL14922948

CCCCC(CC)CCCC(O)CO

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.64
CA2 P00918 2/20 0.47
LMNA P02545 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
CYP3A4 P08684 5/20 0.45
TSHR P16473 3/20 0.45
THRB P10828 1/20 0.44
ATM Q13315 1/20 0.39
USP2 O75604 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 2/20 0.37
CYP2D6 P10635 2/20 0.35
GPR84 Q9NQS5 1/20 0.35
SPHK1 Q9NYA1 1/20 0.35
GMNN O75496 1/20 0.35
POLB P06746 1/20 0.35
THPO P40225 1/20 0.35
MTOR P42345 1/20 0.35
BLM P54132 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL622136 0.91 ALDH1A1 (0.64) ALDH1A1CA2LMNATDP1CYP3A4
SCHEMBL53705 0.86
SCHEMBL2381705 0.86
SCHEMBL16269718 0.86 ALDH1A1 (0.52) ALDH1A1LMNACYP3A4THRBUSP2
SCHEMBL1934981 0.86
Glycerin SCHEMBL27075577 0.84 ALDH1A1 (0.82) ALDH1A1CA2LMNATDP1CYP3A4
SCHEMBL31292800 0.84
SCHEMBL28479835 0.84
SCHEMBL22572340 0.84
Glycerin SCHEMBL278378 0.84 LMNA (0.50) ALDH1A1LMNACYP3A4THRBUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795320-B2 Grafted polymer and use thereof BAUSCH + LOMB IRELAND LIMITED (IE) 2023-10-24 US disclosed
US-11732060-B2 Crosslinked polymeric network and use thereof BAUSCH & LOMB INCORPORATED (US) 2023-08-22 US disclosed
US-20230257485-A1 GLYCOPHOSPHOLIPID POLYMERIC NETWORK AND USE THEREOF JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2023-08-17 US disclosed
US-11673974-B2 Glycophospholipid polymeric network and use thereof BAUSCH & LOMB INCORPORATED (US) 2023-06-13 US disclosed
EP-2099294-B1 COMPOSITIONS GIVAUDAN SA (CH) 2013-05-08 EP disclosed
US-8377126-B2 Renewable polymeric lens coating BAUSCH & LOMB INCORPORATED (US) 2013-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11673974-B2 Glycophospholipid polymeric network and use thereof ALG1, CSGALNACT1, FUT5 ALDH1A1 3218/4885CA2 3651/4885LMNA 2758/4885
US-11732060-B2 Crosslinked polymeric network and use thereof ALG1, CSGALNACT1, CD44 ALDH1A1 1752/4885CA2 3584/4885LMNA 3262/4885
US-20230257485-A1 GLYCOPHOSPHOLIPID POLYMERIC NETWORK AND USE THEREOF ALG1, CSGALNACT1, FUT6 ALDH1A1 4141/4885CA2 2892/4885LMNA 2560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.