Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | MAT2A | P31153 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14923013 | 0.79 | GRM2 (0.41) | LMNA | |
| SCHEMBL10964792 | 0.75 | MAOA (0.53) | RAB9AMEN1NPC1KMT2AALDH1A1 | |
| SCHEMBL7202361 | 0.73 | MEN1 (0.46) | DRD1RAB9AMEN1NPC1KMT2A | |
| SCHEMBL10072935 | 0.73 | RAB9A (0.51) | RAB9AMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9182096 | 0.72 | CXCL12 (0.42) | MAT2ARAB9AMEN1NPC1KMT2A | |
| SCHEMBL27593594 | 0.71 | DRD1 (0.43) | DRD1MAT2ARAB9AMEN1NPC1 | |
| SCHEMBL10964893 | 0.70 | DRD1 (0.41) | DRD1MAT2ARAB9AMEN1NPC1 | |
| SCHEMBL10966521 | 0.70 | DRD1 (0.38) | DRD1MAT2ARAB9AMEN1NPC1 | |
| SCHEMBL19283065 | 0.70 | DRD1 (0.39) | DRD1MAT2ARAB9AMEN1KMT2A | |
| SCHEMBL20471236 | 0.69 | LMNA (0.53) | RAB9AMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118067-B1 | NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | SIENA BIOTECH SPA (IT) | 2013-05-08 | — | — | EP | disclosed |