Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27696866 | 1.00 | LMNA (0.36) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL27696868 | 1.00 | LMNA (0.36) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL27696855 | 1.00 | LMNA (0.36) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL27678296 | 0.98 | SMN1; SMN2 (0.33) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL27484148 | 0.79 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL20968050 | 0.78 | OPRM1 (0.44) | LMNATSHR | |
| SCHEMBL1985690 | 0.78 | CHRNB2 (0.48) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL25887134 | 0.75 | OPRM1 (0.46) | LMNA | |
| SCHEMBL28856626 | 0.75 | CHRNB2 (0.50) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL3778363 | 0.71 | LMNA (0.50) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2365077-B1 | iRNA agents targeting VEGF | ALNYLAM PHARMACEUTICALS INC (US) | 2013-05-08 | — | — | EP | disclosed |