SCHEMBL14925005

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14924970	0.90	MAPT (0.39)	HSP90AA1CA2ALDH1A1HSP90AB1HSP90B1
	SCHEMBL5006538	0.85	TGFBR1 (0.40)	LSSIDO1TDO2IDO2CHKA
	SCHEMBL14924996	0.83	CCR5 (0.39)	LSSCHKACCR5MC4RHSP90AA1
	SCHEMBL5006534	0.83	CHKA (0.35)	LSSIDO1TDO2IDO2CHKA
	SCHEMBL14924995	0.80	HSP90AA1 (0.52)	HSP90AA1HSP90AB1HSP90B1
	SCHEMBL14924998	0.78	HSP90AA1 (0.39)	HSP90AA1ALDH1A1HSP90AB1LMNA
	SCHEMBL5006477	0.78	PDK1 (0.50)	HSP90AA1HSP90AB1HSP90B1
	SCHEMBL14924990	0.78	UCHL3 (0.41)	HSP90AA1HSP90AB1LMNA
	SCHEMBL14381332	0.76	HSP90AA1 (0.39)	IDO1TDO2IDO2HSP90AA1CA2
	SCHEMBL5002989	0.76	HSP90AA1 (0.41)	HSP90AA1HSP90AB1HSP90B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.