Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | CASP7 | P55210 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | METAP1 | P53582 | 2/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | TYMS | P04818 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17899377 | 0.89 | METAP1 (0.56) | CASP1CASP7HSD17B10MAOBMETAP1 | |
| SCHEMBL14925847 | 0.84 | METAP1 (0.60) | MAOBMETAP1PARP10PARP1TYMS | |
| SCHEMBL4135391 | 0.81 | METAP1 (0.50) | MAPK14MAOBMETAP1PARP10PARP1 | |
| SCHEMBL16559372 | 0.80 | CASP1 (0.55) | CASP1CASP7HSD17B10MAPK14MAOB | |
| SCHEMBL7435588 | 0.80 | METAP1 (0.60) | MAPK14MAOBMETAP1PARP10PARP1 | |
| SCHEMBL2317653 | 0.80 | MAPK14 (0.61) | CASP1CASP7HSD17B10MAPK14MAOB | |
| SCHEMBL13877021 | 0.80 | MAPK14 (0.69) | CASP1CASP7HSD17B10MAPK14MAOB | |
| SCHEMBL8797457 | 0.80 | TDP1 (0.64) | MAPK14MAOBMETAP1PARP10PARP1 | |
| SCHEMBL11685442 | 0.77 | SRD5A2 (0.56) | MAPK14METAP1PARP10PARP1ALDH1A1 | |
| SCHEMBL20763966 | 0.77 | NPC1 (0.67) | CASP1CASP7HSD17B10MAOBELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633312-B2 | Dibenzocycloheptatone derivatives and pharmaceutical agents containing said compounds | C-A-I-R BIOSCIENCES GMBH (DE) | 2014-01-21 | — | — | US | disclosed |
| US-20120115862-A1 | DIBENZOCYCLOHEPTATONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | C-A-I-R BIOSCIENCES GMBH (DE) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115862-A1 | DIBENZOCYCLOHEPTATONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | IL1B, NFKBIA, IL1R1 | CASP1 149/4885CASP7 718/4885HSD17B10 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.