SCHEMBL14925855

SCHEMBL14925855

O=C1c2cc(-c3c(-c4ccccc4)cccc3-c3ccccc3)ccc2CCc2ccc(-c3c(-c4ccccc4)cccc3-c3ccccc3)cc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
CES1 P23141 1/20 0.46
MEN1 O00255 1/20 0.43
APAF1 O14727 1/20 0.43
NPC1 O15118 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
THRB P10828 1/20 0.43
XBP1 P17861 1/20 0.43
PTBP1 P26599 1/20 0.43
HTT P42858 1/20 0.43
RAB9A P51151 1/20 0.43
GALK1 P51570 1/20 0.43
BLM P54132 1/20 0.43
SMAD3 P84022 1/20 0.43
KMT2A Q03164 1/20 0.43
ATM Q13315 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10045638 0.88 L3MBTL1 (0.54) L3MBTL1TDP1CES1MEN1APAF1
SCHEMBL10045664 0.84 CLK4 (0.53) L3MBTL1TDP1CES1MEN1APAF1
SCHEMBL10045704 0.84 TYRO3 (0.56) L3MBTL1TDP1CES1MEN1APAF1
SCHEMBL10045703 0.84 TYRO3 (0.56) L3MBTL1TDP1CES1MEN1APAF1
SCHEMBL10045643 0.81 TYRO3 (0.53) L3MBTL1TDP1CES1MEN1APAF1
SCHEMBL10045913 0.80 TDP1 (0.50) L3MBTL1TDP1CES1MEN1NPC1
SCHEMBL22797537 0.78 L3MBTL1 (0.46) L3MBTL1TDP1CES1MEN1APAF1
SCHEMBL14925866 0.78 GRIA1 (0.49) L3MBTL1TDP1CES1MEN1KMT2A
SCHEMBL12177796 0.78 MEN1 (0.41) L3MBTL1MEN1APAF1NPC1LMNA
SCHEMBL10045662 0.77 TDP2 (0.49) L3MBTL1TDP1CES1MEN1APAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130112965-A1 ORGANIC LIGHT-EMITTING DEVICE MATERIAL HAVING DIBENZOSUBERONE SKELETON CANON KABUSHIKI KAISHA (JP) 2013-05-09 US disclosed
US-20130112965-A1 ORGANIC LIGHT-EMITTING DEVICE MATERIAL HAVING DIBENZOSUBERONE SKELETON CANON KABUSHIKI KAISHA (JP) 2013-05-09 US disclosed