SCHEMBL14925866

SCHEMBL14925866

Cc1cccc(C)c1-c1ccc2c(c1)C(=O)c1cc(-c3c(C)cccc3C)ccc1CC2

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA1 P42261 3/20 0.49
CACNG8 Q8WXS5 3/20 0.49
BRD4 O60885 1/20 0.46
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
FYN P06241 1/20 0.39
CLK4 Q9HAZ1 1/20 0.39
DYRK1B Q9Y463 1/20 0.39
MPL P40238 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CES1 P23141 1/20 0.38
TYMS P04818 1/20 0.38
MET P08581 1/20 0.38
HTR7 P34969 1/20 0.38
SRC P12931 1/20 0.37
EDNRB P24530 1/20 0.37
EDNRA P25101 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2340285 0.78 GRIA1 (0.50) GRIA1CACNG8BRD4FYNCLK4
SCHEMBL14925855 0.78 L3MBTL1 (0.50) BRD4TDP1L3MBTL1CLK4DYRK1B
SCHEMBL3630871 0.78 HSD17B1 (0.54) GRIA1CACNG8BRD4MPLTYMS
SCHEMBL14702112 0.78 GRIA1 (0.45) GRIA1CACNG8L3MBTL1CA1CA2
SCHEMBL10045664 0.75 CLK4 (0.53) TDP1L3MBTL1FYNCLK4DYRK1B
SCHEMBL12177761 0.75 GRIA1 (0.45) GRIA1CACNG8L3MBTL1CA1CA2
SCHEMBL10045703 0.74 TYRO3 (0.56) TDP1L3MBTL1CLK4DYRK1BCES1
SCHEMBL10045704 0.74 TYRO3 (0.56) TDP1L3MBTL1CLK4DYRK1BCES1
SCHEMBL30885502 0.74 GRIA1 (0.54) GRIA1CACNG8BRD4HTR7SRC
SCHEMBL10045643 0.71 TYRO3 (0.53) TDP1L3MBTL1CLK4DYRK1BCES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130112965-A1 ORGANIC LIGHT-EMITTING DEVICE MATERIAL HAVING DIBENZOSUBERONE SKELETON CANON KABUSHIKI KAISHA (JP) 2013-05-09 US disclosed
US-20130112965-A1 ORGANIC LIGHT-EMITTING DEVICE MATERIAL HAVING DIBENZOSUBERONE SKELETON CANON KABUSHIKI KAISHA (JP) 2013-05-09 US disclosed